ANALYSIS OF PREVIOUS TUBERCULOSIS TREATMENT AS A PREDISPOSITION FACTOR OF INCREASING NUMBERS OF MULTI DRUG RESISTANCE TUBERCULOSIS (MDR-TB): SKOPING REVIEW

Introduction: The increasing number of patients with resistant tuberculosis requires
attention and efforts for prevention. Resistance causes more expensive cost of treatment,
longer duration of treatment, more severe side effects and decreasing the chance of recovery.
Objective: The aim of this literature review is to identify modifiable factors and nonmodifiable factors for MDR-TB. Methodology/Approach: This study applies scoping
review method of JBI (Joanna briggs Institute) by using 5 databases: Scopus, Ebscohost,
Proquest, Science direct and google scholar publication 2015-2021. keywords for MDR-TB
search, predisposing factors, previously treatment and adult. Results: The most
predisposing factor that strongly led to MDR-TB was the previous tuberculosis treatment
status. Some of the possibilities that can occur is when people with tuberculosis undergo
failure treatment or interruption of treatment, disobedience, lack of supervision, unclear or
inadequate instructions about treatment and drug side effects. Conclussion: The cause of
MDR-TB which can be modified and cannot be modified is very important to know. The
government as a policy maker can use the results of this research to strengthen tuberculosis
control programs and prevention of resistant tuberculosis